Is our universe unique or one of many? What happened before the Big Bang? Why is there something rather than nothing? Physicists and cosmologists are closing in on how the universe operates at its very core. But even with powerful telescopes and particle accelerators pushed to their limits, experimenters struggle to keep up as theoreticians march forward, leaving grand theories untested. Some argue that if these deep questions can’t be answered empirically, they’re not relevant to science. Are they right? Join world-leading cosmologists, philosophers and physicists as they tackle the profound questions of existence.